Table 1. Gene functions overrepresented in ERβ2 expressing PC3 cells.
| Gene Ontology-Biological Process | Genes Regulated | Percent-of-genes Included in function | P—Value |
|---|---|---|---|
| Gene expression | 32 | 4 | 1.80E-06 |
| Response to hypoxia | 17 | 6 | 8.00E-06 |
| Small molecule metabolic process | 44 | 3 | 0.000089 |
| Cellular protein metabolic process | 20 | 4 | 0.00011 |
| Negative regulation of cell proliferation | 20 | 4 | 0.00024 |
| Ribosome biogenesis | 8 | 9 | 0.00024 |
| Activation of cysteine-type endopeptidase activity involved in apoptotic process | 8 | 8 | 0.00033 |
| Apoptotic mitochondrial changes | 4 | 21 | 0.00039 |
| Glycogen biosynthetic process | 4 | 20 | 0.00048 |
| Positive regulation of lipid biosynthetic process | 3 | 33 | 0.00052 |
| Protein folding | 12 | 5 | 0.00059 |
| Glucose metabolic process | 9 | 7 | 0.00067 |