Fig 2. Amounts of proinflammatory cytokines and chemokines released from brain slices of young adult (y, open bars) and aged (a, closed bars) mice.
(A-D) Concentrations of TNF-α (A), IL-6 (B), CCL2 (C) and CXCL1 (D) were determined in media of slices, which were either kept untreated or treated with 1 μg/ml LPS for 24 h. Cytokine and chemokine concentrations determined for individual slices were normalized to the corresponding slice area. ***, p<0.001; **, p<0.01; *, p<0.05; n.s., not significantly different.
