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Concentrations of IL-6 (A), CCL2 (B) and CXCL1 (C) were determined for young adult (y, open bars) and aged (a, closed bars) mice. Cytokine/chemokine concentrations determined in media from slices treated with 10 μM PSB0739 (PSB) were normalized to those from control slices kept untreated for 24 h. ***, p<0.001; **, p<0.01; *, p<0.05; n.s., not significantly different.
