Table 1. Protein coding genes in genomic regions of CNVs detected in HAB/LAB and CD-1 mice.
| Gene | CNV (in CD-1 mice) | Association | ||||||
|---|---|---|---|---|---|---|---|---|
| Symbol | MGI ID | Chr | Start | End | Chr | Start | End | nominal p-value |
| Sirpb1a | 2444824 | 3 | 15371819 | 15426504 | 3 | 15340258 | 15819607 | 0.01213 |
| Sirpb1b | 3779828 | 3 | 15495754 | 15575065 | 3 | 15340258 | 15819607 | 0.01213 |
| Sirpb1c | 3807521 | 3 | 15695145 | 15748528 | 3 | 15340258 | 15819607 | 0.01213 |
| Skint4 | 2444425 | 4 | 111744621 | 111840681 | 4 | 111745396 | 112286229 | 0.04514 |
| Skint3 | 3045331 | 4 | 111904850 | 111973073 | 4 | 111745396 | 112286229 | 0.04514 |
| Skint9 | 3045341 | 4 | 112058574 | 112106590 | 4 | 111745396 | 112286229 | 0.04514 |
| Skint6 | 3649262 | 4 | 112908844 | 112959568 | 4 | 112348832 | 113968233 | 0.02412 |
| Skint5 | 3650151 | 4 | 113613249 | 113672102 | 4 | 112348832 | 113968233 | 0.02412 |
| Skint11 | 2685415 | 4 | 113835989 | 113917633 | 4 | 112348832 | 113968233 | 0.02412 |
| C230055K05Rik | 2441896 | 5 | 105242188 | 105288830 | 5 | 105034912 | 105359320 | 0.03593 |
| Tcp10b | 98542 | 17 | 13253977 | 13275092 | 17 | 13259210 | 13301725 | 0.07376 |
| Gm10512 | 3642173 | 17 | 13397908 | 13399077 | 17 | 13398037 | 13649185 | 0.07250 |
| Smok2a | 1351487 | 17 | 13414054 | 13420524 | 17 | 13398037 | 13649185 | 0.07250 |
| Smok2b | 3037705 | 17 | 13421718 | 13430055 | 17 | 13398037 | 13649185 | 0.07250 |
| Gm9880 | 3711246 | 17 | 13547438 | 13569717 | 17 | 13398037 | 13649185 | 0.07250 |
All genes listed overlap both CNVs in HAB/LAB mice detected with aCGH, JaxMDGA and NGS, and CNVs in CD-1 mice which were best associated with the time the animals spent on the open arm of the EPM (nominal p-value < 0.1).