Table 1. Enzymatic activities and lectin binding in the cervicovaginal fluid of premenopausal women, stratified by Nugent scores.

	Nugent Score
	Normal (n = 89)	Intermediate (n = 23)	Bacterial Vaginosis (n = 23)	P-value 2
	Nugent score 0–3	Nugent score 4–6	Nugent score 7–10
Glycosidases
Sialidase	0 (0–6.90)	0 (0–6.21)	3.88 (0–9.85)	<0.001
α-fucosidase	0.33 (0–2.64)	0.33 (0–0.97)	0.29 (0–1.31)	0.83
α-galactosidase	0.31 (0–4.79) 4	0 (0–2.50)	0.19 (0–3.47) 4	0.003
β-galactosidase	0 (0–23.84)	0 (0–2.12)	0.17 (0–1.73)	0.006
α-glucosidase	5.91 (0–67.02)	8.59 (0–41.21)	14.31 (0–61.27)	0.042
β-glucosidase	0 (0–3.96)	0 (0–0.91)	0 (0–0.45)	0.23
Lectin binding
Maakia amurensis	0.15 (0.07–0.56)	0.14 (0.11–0.28)	0.13 (0.08–0.31)	0.28
Sambucus nigra	0.16 (0.05–0.81)	0.19 (0.08–0.33)	0.11 (0.06–0.20)	0.003
Griffithsin 1	10.36 (0–35.39)	8.48 (0.89–33.38)	3.14 (0.97–11.92)	<0.001

¹Data are presented as medians (range) in μMoles substrate hydrolyzed per min per mg protein. Griffithsin is measured as pg/ng protein.

² P-value from Kruskal-Wallis test.

⁴ P-value = 0.04 from Mann-Whitney U test comparing normal women to women with bacterial vaginosis for alpha galactosidase.