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. 2015 May 26;10(5):e0127956. doi: 10.1371/journal.pone.0127956

Table 1. Performance of urine LAM test overall and stratified by HIV status compared with gold standard of bacteriologically-confirmed TB.

Group Prevalence of TB Prevalence of positive LAM Sensitivity Specificity PPV NPV
% (n) % (n) % (95% CI) % (95% CI) % (95% CI) % (95% CI)
Overall (n = 844) 3.9 (33) 0.6 (5) 3.0 (0.1–15.8) 99.5 (98.7–99.9) 20.0 (0.5–71.6) 96.2 (94.7–97.4)
HIV-positive (n = 212) 6.6 (14) 1.9 (4) 7.1 (0.2–33.9) 98.5 (95.6–99.7) 25.0 (0.6–80.6) 93.8 (89.5–96.6)
HIV-negative (n = 632) 3.0 (19) 0.2 (1) 0 (0–17.6) 99.8 (99.1->99.9) 0 (0–97.5) 97.0 (95.3–98.2)

NPV = negative predictive value; PPV = positive predictive value; CI confidence interval

27 participants with possible TB have been excluded from this analysis