Fig 1. Route of MPP⁺ infusion.

(A) Designed route of MPP⁺ infusion in a coronal section of the rhesus monkey brain [47]. The route (black line) can penetrate both SNc and striatum (particularly the putamen, Pu). Black dots in the right panel indicate the ten sites of MPP⁺ infusion. (B) Glycerol tubes (blue lines) detectable in MRI serve as markers. The final plane (yellow plane) of the infusion route (yellow line) is determined based on the distance between the coronal plane of targeted SNc and the coronal plane (blue plane) of glycerol marker (blue lines).