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. Author manuscript; available in PMC: 2015 May 26.
Published in final edited form as: Annu Rev Biophys. 2014;43:381–408. doi: 10.1146/annurev-biophys-051013-022653

Figure 4.

Figure 4

Correct cargos stabilize the early intermediate and mediate faster rearrangement to the closed complex, and thus enabling faster assembly of a stable SRP-FtsY complex. (a) Summary of the equilibrium dissociation constants (Kd) of the early intermediate formed with different cargos (adapted from Fig. 2C in ref. (160)). (b) Summary of the rate constants for the conformational rearrangement from the early to closed complex mediated by the different cargos (adapted from Fig. 2G in ref. (160)). (c) Rate constants for assembly of the stable, GTP-dependent closed complex mediated by the different cargos (adapted from Fig. 3C in ref. (160)).