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Summary of phenotypes observed in Entamoeba histolytica HM-1: IMSS parasites with silenced EhROM1 expression (T-EhROM1-s) versus parasites over-expressing the EhROM1-SA gene (EhROM1-SA).
| Phenotype | EhROM1-SA | T-EhROM1-s |
|---|---|---|
| Cytotoxicity | ++ | ++ |
| Hemolytic activity | ++ | ++ |
| Erythrophagocytosis | − | + |
| Pinocytosis | ++ | + |
| Motility | +++ | +++ |
| Chemotaxis | +++ | ++ |
| Complement resistance | − | − |
+++ strong defect, ++ considerable defect, + moderate defect, − no change
