. Author manuscript; available in PMC: 2016 Jun 1.

Published in final edited form as: Osteoarthritis Cartilage. 2015 Feb 3;23(6):949–956. doi: 10.1016/j.joca.2015.01.014

Table 1.

Summary of inhibitors used in this study.

Inhibitor	IC₅₀	Dose (µM)	Inhibitor Target
LY294002	1.4µM	5	pan-PI-3 kinase

A66	32nM	10	PI-3 kinase-α

TGX-101	10nM	10	PI-3 kinase-β

AS-252424	33nM	10	PI-3 kinase-γ

CAL-101	65nM	10	PI-3 kinase-δ

PD98059	2µM	30	MEK (ERK)

SP600125	40nM	20	JNK

SB203580	0.3–0.5µM	10	p38

Ruxolitinib	3.3/2.8nM	10	JAK1/2 (STAT3)