Fig. 4.
Histopathology of the colons of mice from the BP/DSS group at weeks 4, 7, 9 and 11. Neoplastic lesions including tubular adenoma and polypoid tubular adenocarcinoma can be seen in the distal part of the colonic mucosa at week 4 (A). Thereafter, the size of the neoplastic lesions gradually increases with time at weeks 7 (B), 9 (C) and 11 (D). H& E stain.