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. 2014 Nov 13;16(3):579–588. doi: 10.1208/s12249-014-0236-2

Table IV.

Modeling of Dissolution Profiles

Tablet system Zero-order First-order Higuchi model Korsmeyer-Peppas model Hixson-Crowell model
R 2 K R 2 K R 2 K R 2 n K R 2 K
Core + outer layer 0.892 0.145 0.914 −0.006 0.958 3.773 0.971 0.281 20.04 0.944 −0.012
Core 0.892 0.145 0.933 −0.001 0.958 3.773 0.917 1.23 0.05 0.920 −0.002