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| Cat, pig, wild carnivore, and monkey bites |
| Presentation more than 8 h after bite |
| Bites involving hands and feet, face and genitalia |
| Moderate or severe wounds, deep puncture wounds that may have penetrated joint spaces, bones or tendons, suspected fractures |
| Primarily closed wounds/wounds requiring surgical repair |
| Diabetes mellitus |
| Asplenic patient |
| Immunocompromised (disease or drugs) |
| Elderly |
| Prosthetic heart valve |
