Table 8.

Summary of empiric antibiotic treatment for facial bite wounds—therapeutic regimen [3, 45]

	Dog	Cat	Human
Onset of symptoms	12–48 h post injury	7–18 h post injury	12–36 h post injury
Oral therapy: Amoxicillin-clavulanate. For penicillin allergy, clindamycin plus either ciprofloxacin or TMP-SMX
Intra-venous therapy Ampicillin-sulbactam, or ticarcillin-clavulanate, or cefoxitin. Any of this plus amino glycoside for bite wounds heavily contaminated with soil or inflicted by hospitalized patients. For penicillin allergy, clindamycin plus either ciprofloxacin or TMP-SMX
Duration of therapy: 7–14 days for soft tissue infection; 3 weeks or more for bone involvement

TMP/SMX trimethoprim-sulphamethoxazole