Table 1.

Comparison between two CE-marked, FDA-approved leadless, continuous electrocardiographic patch devices and the standard Holter monitor.

	ZIO® XT	SEEQ™ (formerly NUVANT) MCT	Holter monitor
Manufacturer	iRhythm Technologies, Inc.	Medtronic, Inc. (Corventis)*	Variable
Data storage capacity	14 days	7.5 days; up to 30 days with deployment of multiple units	24–72 h
Method of application	Timed adhesive	Timed adhesive	Multiple detachable leads and adhesive pads
Number of ECG channel(s)	1	1	Multiple (typically, 3 and up to 12)
ECG resolution (bits)	10	16	Variable
ECG sample rate (Hz)	200	200	Variable
Detection range of heart rate (bpm)	0 to >300	25–250	Variable
Symptom trigger	Yes	Yes	Yes
Water resistant	Yes	Yes	No
Data transmission or upload mechanism	Mail-in return of device for data retrieval	Bluetooth between sensor and transmitter, cellular transmission between transmitter and server	In-house data download in clinic
Preliminary data processing, management and reporting	Medicare certified independent diagnostic testing facility, certified technician	Medicare certified independent diagnostic testing facility, certified technician	Clinic/Hospital-based technician
Weight (g)	34	50	Variable (average 100–150, min. 62)
Dimensions (mm)	123 × 53 × 10.7	160 × 60 × 15	100 × 60 × 25 (average)
Associated components	None	Wireless transmitter, battery charger	Leads, recorder, straps
Device cost§	Variable (US$329)†	Variable (US$718)¶	Variable (US$600 to $6000+)

For other multi-lead, multi-channel ambulatory telemetry systems, please refer to a review by Mittal et al. (You et al., 2012).

^*Acquired by Medtronic plc.

^§Excluding clinic, technician and other fees.

^†Direct self-pay price.

^¶Medicare negotiated price, qualified patient pays 20%.