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Decision curve analysis demonstrating the higher net benefit of the 4Kscore Test® (OPKO Lab, Nashville, TN) (green line) compared with biopsy all (dashed line) and the Prostate Cancer Prevention Trial Risk Calculator (PCPTRC) 2.0 (yellow line) across all relevant risk threshold values for clinical decision making from the US Validation Study. Adapted from Parekh D, et al.36
