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. 2015 Apr 24;6(6):443–452. doi: 10.1007/s13238-015-0154-4

Table 1.

Activation and steady-state inactivation characteristics of Nav1.8 currents

Voltage-dependent activation Steady-state inactivation
n V1/2 (mV) k m (mV) n V1/2 (mV) k m (mV)
Control 19 −7.05 ± 2.40 3.25 ± 0.83 30 −16.89 ± 0.41 4.54 ± 0.28
100 nmol/L BmK I 10 −9.75 ± 2.31 3.39 ± 0.60 7 −19.52 ± 0.83 4.49 ± 0.51
500 nmol/L BmK I 5 −18.77 ± 2.66*** 4.50 ± 0.83 5 −23.42 ± 0.90* 5.98 ± 0.60
1 μmol/L BmK I 6 −21.93 ± 1.25*** 5.34 ± 0.51 7 −23.94 ± 0.68*** 6.51 ± 0.45

Note: *  P < 0.05, ***  P < 0.001, compared with control group. Student’s t-test. Data are mean ± SEM