Figure 2.

Cell-to-cell variability of HSF1 activation in response to environmental challenges is increased in schizophrenia neural progenitor cells. The number of cells that are in the levels of excess or very little activation of HSF1 was increased in the schizophrenia cells (Hashimoto-Torii et al., 2014; Brennand et al., 2015). These outlier cells may be at the risk of manifesting pathophysiological features (indicated by the cells surrounded by broken lines).