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. 2015 May 27;5:10517. doi: 10.1038/srep10517

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Time series of the hydrophobic contacts (HC) number between the HIV-1 PR and (a) APV or (b) DRV inhibitor. A representative structure of HIV-1 PR containing the hydrophobic interactions among the flap, 80 s (80’s) loop, and APV inhibitor is shown in left panel.