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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Biochem Biophys Res Commun. 2015 Mar 18;460(2):434–438. doi: 10.1016/j.bbrc.2015.03.051

Figure 2. Representation of the E-curves describing the trajectory of the minimum of each domain as a function of force.

Figure 2

The free energy for eight tandem repeats displays nine local minima, corresponding to 0 – 8 unfolded domains. The global minimum of the free energy shifts from 0 domains unfolded to 8 domains unfolded as the force is increased from 4 to 18 pN. E-curves are represented by dashed lines that track the free energy minima through different forces.