Table 2.
No. | Pathway ID | Pathway description | Target genes with pathway annotation, n (%) | P value |
1 | hsa05200 | Pathways in cancer | 179 (2.37) | 5.50 ×10-3 |
2 | hsa04060 | Cytokine-cytokine receptor interaction | 152 (2.01) | 4.00 × 10-4 |
3 | hsa04010: | MAPK signaling pathway | 146 (1.93) | 1.13 × 10-2 |
4 | hsa04080 | Neuroactive ligand-receptor interaction | 139 (1.84) | 1.81 × 10-2 |
5 | hsa04510 | Focal adhesion | 121 (1.60) | 2.00 × 10-4 |
6 | hsa04810 | Regulation of actin cytoskeleton | 116 (1.54) | 3.79 × 10-2 |
7 | hsa04062 | Chemokine signaling pathway | 107 (1.42) | 5.60 × 10-3 |
8 | hsa04020 | Calcium signaling pathway | 95 (1.26) | 5.88 × 10-2 |
9 | hsa04142 | Lysosome | 72 (0.95) | 2.3 × 10-3 |
10 | hsa04670 | Leukocyte transendothelial migration | 68 (0.90) | 2.36 × 10-3 |