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. 2015 May 28;21(20):6317–6328. doi: 10.3748/wjg.v21.i20.6317

Table 9.

Mutation case numbers and rates of TP53 in hepatocellular carcinoma etiologies

Viral background GOF mutation cases (n) Mutation cases (n) Total cases (n) GOF mutation rate (%) Non-GOF mutation rate (%) Total mutation rate (%)
HBV 35 321 819 4.27 34.92 39.19
HCV 9 101 398 2.26 23.12 25.38
HBV and HCV 0 18 41 0.00 43.90 43.90
non-viral 7 60 346 2.02 15.32 17.34

GOF: Gain-of-function; HBV: Hepatitis B virus; HCV: Hepatitis C virus.