Table 1.
Hypertensive Term | Definition | Comments |
---|---|---|
Resistant hypertension | Uncontrolled BP despite maximal effective dosing of ≥3 medications of different classes, one ideally being a diuretic41 | Includes patients controlled on ≥4 medications |
Apparent resistant hypertension | Meeting criteria for resistant HTN, yet unable to exclude pseudoresistance62 | Reported in observational studies |
Pseudoresistance | Uncontrolled office BP while receiving ≥3 medications in the setting of medication nonadherence, improper BP measurement technique, and/or white coat HTN | Presumed to contribute to as much as 50% of resistant hypertension62 |
White coat hypertension | Uncontrolled office BP with a controlled overall average BP by 24-hr ABPM (<130/80 mm Hg) or home BP < 135/85 mm Hg7 | |
Masked uncontrolled hypertension | Controlled office BP (<140/90 mm Hg) with an elevated overall average BP by 24-hr ABPM (>130/80 mm Hg) or home BP > 135/85 mm Hg7 | Present in as many as 40%–70% of patients with CKD and HTN9,10 |
Dipping | Fall in nocturnal systolic and diastolic BP of >10% of daytime values7 | |
Nondipping and rising | No reduction or an increase in nocturnal systolic and/or diastolic BP7 | |
Refractory hypertension | Uncontrolled BP despite maximal medical therapy (ie, ≥5 antihypertensive medications at maximal effective dosing and of different class) |
Abbreviations: ABPM, ambulatory blood pressure monitoring; BP, blood pressure; CV, cardiovascular; HTN, hypertension.