Table 2.
Chemokine receptor expression and ligand responses on mouse NKT cells.
| Receptor | Expression (%)a | Chemotactic responseb |
Reference | ||||
|---|---|---|---|---|---|---|---|
| Spleen | Liver | Bone Marrow | Blood | Other | |||
| CCR1 | n.d. | − | − | − | − | (88) | |
| CCR2 | 23 | − | − | − | − | (88, 141) | |
| CCR3 | n.d. | − | − | − | − | (88) | |
| CCR4 | n.d. | − | − | − | − | Lung: ++ | (88, 108) |
| CCR5 | 20–60 | − | − | − | − | (88, 93, 141) | |
| CCR6 | PLN: 70–80 | − | − | − | − | PLN: ++ | (54, 88) |
| CCR7 | Thymus: 15–60 | + | − | + | + | (88) | |
| CCR8 | n.d. | − | (88) | ||||
| CCR9 | 18–80 | − | (88, 98, 141) | ||||
| CCR10 | n.d. | − | (88) | ||||
| CXCR2 | n.d. | − | − | − | − | (88) | |
| CXCR3 | 80–96 | ++ | ++ | ++ | ++ | (88) | |
| CXCR4 | 55–58 | + | + | ++ | ++ | (88) | |
| CXCR5 | Spleen: 35–38 | + | − | − | − | (88) | |
| CXCR6 | 92–94 | + | n.d. | n.d. | n.d. | Thymus: + | (88, 91) |
| CX3CR1 | n.d. | − | − | − | − | (88) | |
| XCR1 | n.d. | − | − | − | − | (88) | |
aRange in reported frequency of receptor positive NKT cells.
bNet chemotactic migration: − (did not respond), + (<25%), and ++ (>25%).
n.d., not determined; PLN, peripheral lymph nodes.