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Oral immunizations increase antibody production. Fish were immunized by injectable vaccines as primo-vaccination and later as booster immunization by the oral route against SRS (A) and ISAv (B) infections. The IgM level was followed up to 3000 degree-days. The arrow indicates the time-point where the oral vaccine was administrated. Samples were statistically analyzed by one-way ANOVA – Dunnet post-test. (SRS 120 fish/point, ISAv 65 fish/per point) *p < 0.05; **p < 0.01; ***p < 0.001.
