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. Author manuscript; available in PMC: 2015 May 27.
Published in final edited form as: JAMA Ophthalmol. 2014 Mar;132(3):265–271. doi: 10.1001/jamaophthalmol.2013.7649

Table 4.

Unadjusted and Adjusted Analysis of Factors Associated With Visual Acuity in Patients With Optic Pathway Gliomas

Variable Unadjusted Coefficient Adjusted Coefficient 95% CI P Value
Mean RNFL −0.011a −0.001 −0.013 to −0.008 <.001
Age −0.022 −0.027 −0.059 to 0.005 .10
Diagnosis
 NF1 Reference Reference
 Sporadic 0.505a 0.064 −0.027 to 0.156 .17
Glioma location
 Absent Reference Reference
 Optic nerve 0.126 0.053 −0.171 to 0.276 .64
 Optic chiasmb 0.209 −0.160 −0.394 to 0.074 .18
 Optic tractsb 0.228 −0.078 −0.316 to 0.160 .52
Treatment status
 No treatment Reference Reference
 Chemotherapy 0.284a 0.084 −0.083 to 0.252 .32

Abbreviations: NF1, neurofibromatosis type 1; RNFL, retinal nerve fiber layer.

a

Denotes P < .01 in unadjusted analysis.

b

Includes structures anterior to this location.