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. 2015 Jun 1;88(2):167–179.

Table 2. Risk factors for recurrence of basal cell carcinoma from the National Comprehensive Cancer Network (NCCN) [65].

H&P Low-Risk High-Risk
Location/size Area L < 20 mm Area L ≥ 20 mm
Area M < 10 mm Area M ≥ 10 mm
Area H < 6 mma Area H ≥ 6 mma
Borders Well defined Poorly defined
Primary vs. recurrent Primary Recurrent
Immunosuppression (-) (+)
Site of prior RT (-) (+)
Pathology
Subtype Nodular, superficial Aggressive-growth pattern
Perineural involvement (-) (+)

Area L = trunk and extremities. Area M = cheeks, forehead, scalp, and neck. Area H = “mask areas” of face (central face, eyelids, eyebrows, periorbital, nose, lips [cutaneous and vermilion], chin, mandible, preauricular and postauricular skin/sulci, temple, ear), genitalia, hands, and feet. aLocation independent of size may constitute high risk in certain clinical settings.