Table 2. Risk factors for recurrence of basal cell carcinoma from the National Comprehensive Cancer Network (NCCN) [65].
H&P | Low-Risk | High-Risk |
Location/size | Area L < 20 mm | Area L ≥ 20 mm |
Area M < 10 mm | Area M ≥ 10 mm | |
Area H < 6 mma | Area H ≥ 6 mma | |
Borders | Well defined | Poorly defined |
Primary vs. recurrent | Primary | Recurrent |
Immunosuppression | (-) | (+) |
Site of prior RT | (-) | (+) |
Pathology | ||
Subtype | Nodular, superficial | Aggressive-growth pattern |
Perineural involvement | (-) | (+) |
Area L = trunk and extremities. Area M = cheeks, forehead, scalp, and neck. Area H = “mask areas” of face (central face, eyelids, eyebrows, periorbital, nose, lips [cutaneous and vermilion], chin, mandible, preauricular and postauricular skin/sulci, temple, ear), genitalia, hands, and feet. aLocation independent of size may constitute high risk in certain clinical settings.