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. 2014 Dec 2;23(2):363–373. doi: 10.1038/mt.2014.198

Figure 3.

Figure 3

Femoropatellar IGF-I concentration and synovial fluid composition (mean ± SEM) over time following chondrocyte implantation. (a) IGF-I concentration in the synovial fluid of joints treated with rAAV5-IGF-I transduced chondrocytes was significantly increased over rAAV5-GFP treated joints or fibrin-treated joints at days 4 and 7 (*P < 0.05). (b) Nucleated cell count (NCC) was significantly increased over baseline in rAAV5-GFP and fibrin-treated joints at day 4 (*P < 0.05). NCC in rAAV5-GFP treated joints was also significantly increased over joints treated with rAAV5-IGF-I chondrocytes and naive chondrocytes at day 4 (**P < 0.05). (c) Total protein (g/dl) increased in all treatment groups postoperatively with no significant differences between groups.