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. 2014 Nov 4;23(2):226–234. doi: 10.1038/mt.2014.199

Figure 4.

Figure 4

AAV2.Flt23k inhibits laser-induced choroidal neovascularization (CNV) in a mouse model. (a) Representative images of laser-induced CNV lesions on RPE/choroidal flatmounts in mice show a reduced volume of CNV lesions in AAV2.Flt23k treated mice compared to untreated mice and mice treated with either PBS or AAV2.AcGFP. (b) CNV volume quantification demonstrates a significant reduction in CNV volumes in mice treated with AAV2.Flt3k compared to untreated, and both PBS and AAV2.AcGFP treated mice. Scale bar: 30 µm. Error bar represents the SD. P values were calculated using the two-tailed student's T-test.