Figure 6.

Relapsed tumors show decreased expression of markers that define immune cell recruitment. Regressed, relapsed, and progressed tumors as defined in Figure 3a were collected and analyzed for the expression of molecules involved in immune cell recruitment. RNA isolation, processing and data analysis are described in Supplementary Text. Analyses were restricted to chemoattractants, ligands for leukocyte rolling and ligands for leukocyte adhesion. Expression of genes in either regressed or relapsed tumors (white and black bars, respectively) is presented as fold change in relation to progressed tumors. Calculations were based on mean values, n = 3, per tumor type. Statistical significances for all three types of molecules were calculated with Sign tests.