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. 2015 May 20;5:10035. doi: 10.1038/srep10035

Figure 4. mRNA expression profile of key components of extRAAS across tissues.

Figure 4

The relative abundance of gene transcripts in each tissue is expressed as the mean expression centile rank (MCR) across data sets (Mean ± SEM). (a-b). Renin receptors: ATP6AP2, ATPase, H + transporting, lysosomal accessory protein 2; IGF2R, insulin-like growth factor 2 receptor. c. ACE2, angiotensin converting enzyme type 2. (d-e). Angiotensin peptides receptors: AGTR2, angiotensin II type 2 receptor; MAS1, Ang (1–7) receptor; LNPEP, angiotensin IV receptor. PBMC, peripheral blood mononuclear cells; SAE, small airways epithelium; LAE, large airways epithelium; Omental, Omental adipose tissue; Subcut, sub-cutaneous adipose tissue; Sk. Muscle, Skeletal muscle. Expression profiles for the other investigated tissues are provided in supplemental data.