Table 1.
Clinical and laboratory features in 145 patients with chronic myelomonocytic leukemia
| Age in years, median (range) | 63(18–85) |
|---|---|
| Males; n (%) | 98(68) |
| Hemoglobin g/L, median (range) | 88.0(43.0–166.0) |
| WBC (109/L), median (range) | 21.88(3.01–117.57) |
| ANC (109/L), median (range) | 7.07(0.30–66.91) |
| AMC (109/L), median (range) | 3.58(1.02–57.72) |
| Platelets (109/L), median (range) | 78(4–1001) |
| FAB subtypes, n (%) | |
| Myelodysplastic, MD | 51(35) |
| Myeloproliferative, MP | 94(65) |
| WHO subtypes, n (%) | |
| CMML-1 | 84(58) |
| CMML-2 | 61(42) |
| Mutational status | |
| ASXL1, n (%) | 65(45) |
| SETBP1, n (%) | 26(18) |
| TET2, n (%) | 47(32) |
| SRSF2, n (%) | 42(29) |
| aAcute leukemic transformation; n (%) | 18(14) |
| aDeaths; n (%) | 71(56) |
aData of acute leukemic transformation and deaths were limited to 127 patients because of 15 cases of limited updating and 3 cases of transplantation