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. 2015 May 27;15:433. doi: 10.1186/s12885-015-1459-7

Table 2.

Distribution of SNPs in IL-27 among patients and controls and their association with bladder cancer risk

		rs153109				rs17855750
Model	Genotype	Controls	patients	OR (95 % CI)^a	P value^a	Genotype	Controls	patients	OR (95 % CI)^a	P value^a
Model	Genotype	N = 499 (%)	N = 332 (%)	OR (95 % CI)^a	P value^a	Genotype	N = 499 (%)	N = 332 (%)	OR (95 % CI)^a	P value^a
Codominant	AA	229 (45.9)	127 (38.2 %)	1.00 (reference)	0.075	TT	421 (84.4)	275 (82.8 %)	1.00 (reference)	0.022
	AG	204 (40.9)	160 (48.2 %)	1.41 (1.05–1.92)		TG	78 (15.6)	53 (16.0 %)	0.97 (0.66–1.42)
	GG	66 (13.2)	45 (13.6 %)	1.23 (0.79–1.89)		GG	0	4 (1.2 %)	0.00 (0.00-NA)
Dominant	AA	229 (45.9)	127 (38.2 %)	1.00 (reference)	0.029	TT	421 (84.4)	275 (82.8 %)	1.00 (reference)	0.57
Dominant	AG/GG	270 (54.1)	205 (61.8 %)	1.37 (1.03–1.82)	0.029	TG/GG	78 (15.6)	57 (17.2 %)	0.90 (0.62–1.31)	0.57
Recessive	AA/AG	433 (86.8)	287 (86.5 %)	1.00 (reference)	0.9	TT/TG	499 (100)	328 (98.8 %)	1.00 (reference)	0.006
Recessive	GG	66 (13.2)	45 (13.6 %)	1.03 (0.68–1.54)	0.9	GG	0 (0)	4 (1.2 %)	0.00 (0.00-NA)	0.006
Overdominant	AA/GG	295 (59.1)	172 (51.8 %)	1.00 (reference)	0.037	TT/GG	421 (84.4)	279 (84.0 %)	1.00 (reference)	0.92
Overdominant	AG	204 (40.9)	160 (48.2 %)	1.35 (1.02–1.79)	0.037	TG	78 (15.6)	53 (16.0 %)	0.98 (0.59–1.19)	0.92
	Allele
	A	662 (66.3)	414 (62.3)	1.19 (0.97–1.46)	0.096	T	920 (92.2)	603 (90.8)	1.20 (0.84–1.70)	0.317
	G	336 (33.7)	250 (37.7)	1.19 (0.97–1.46)	0.096	G	78 (7.8)	61 (9.2)	1.20 (0.84–1.70)	0.317

N corresponds to the number of individuals

^aAdjusted by age, sex and smoking status

Boldfaced values indicate a significant difference at the 5 % level