Skip to main content

View full-text article in PMC

. 2015 May 27;15:433. doi: 10.1186/s12885-015-1459-7

Table 3.

Distribution of SNPs in IL-27 among NMIBC and MIBC patients

		rs153109				rs17855750
Model	Genotype	NMIBC	MIBC	OR (95 % CI)^a	P value^a	Genotype	NMIBC	MIBC	OR (95 % CI)^a	P value^a
Model	Genotype	N = 176 (%)	N = 156 (%)	OR (95 % CI)^a	P value^a	Genotype	N = 176 (%)	N = 156 (%)	OR (95 % CI)^a	P value^a
Codominant	AA	66 (37.5 %)	61 (39.1 %)	1.00 (reference)	0.99	TT	149 (84.7 %)	126 (80.8 %)	1.00 (reference)	0.076
	AG	87 (49.4 %)	73 (46.8 %)	1.04 (0.60–1.81)		TG	26 (14.8 %)	27 (17.3 %)	0.53 (0.26–1.09)
	GG	23 (13.1 %)	22 (14.1 %)	1.02 (0.46–2.27)		GG	1 (0.6 %)	3 (1.9 %)	0.15 (0.01–1.84)
Dominant	AA	66 (37.5 %)	61 (39.1 %)	1.00 (reference)	0.88	TT	149 (84.7 %)	126 (80.8 %)	1.00 (reference)	0.042
Dominant	AG/GG	110 (62.5 %)	95 (60.9 %)	1.04 (0.62–1.75)	0.88	TG/GG	27 (15.3 %)	30 (19.2 %)	2.04 (1.02–4.17)	0.042
Recessive	AA/AG	153 (86.9 %)	134 (85.9 %)	1.00 (reference)	0.99	TT/TG	175 (99.4 %)	153 (98.1 %)	1.00 (reference)	0.14
Recessive	GG	23 (13.1 %)	22 (14.1 %)	1.00 (0.48–2.09)	0.99	GG	1 (0.6 %)	3 (1.9 %)	0.17 (0.01–2.07)	0.14
Overdominant	AA/GG	89 (50.6 %)	83 (53.2 %)	1.00 (reference)	0.88	TT/GG	150 (85.2 %)	129 (82.7 %)	1.00 (reference)	0.1
Overdominant	AG	87 (49.4 %)	73 (46.8 %)	1.04 (0.63–1.73)	0.88	TG	26 (14.8 %)	27 (17.3 %)	0.55 (0.27–1.13)	0.1
	Allele
	A	219 (62.2)	195 (62.5)	0.99 (0.72–1.35)	0.94	T	324 (92.0)	279 (89.4)	1.37 (0.81–2.32)	0.28
	G	133 (37.8)	117 (37.5)	0.99 (0.72–1.35)	0.94	G	28 (8.0)	33 (10.6)	1.37 (0.81–2.32)	0.28

N corresponds to the number of individuals

^aAdjusted by age, sex and smoking status

Boldfaced values indicate a significant difference at the 5 % level