Fig. 2.

Differential modulation of tissue injuries in CLP mice pre-conditioned with super-low or low dose LPS. Vital organs were collected from CLP mice pre-conditioned with either PBS, 5 ng/kg LPS, or low dose (50 μg/kg) LPS. (A) Frozen kidney sections were stained with H&E. G: glomerulus; T: tubular cells; arrow: PMN. Scale bar = 50 μm. (B) Frozen lung sections (5 μm) were stained with H&E. A: Alveolus; B: Bronchiole; V: Blood vessels; arrow: PMN. Scale bar = 50 μm. (C) Frozen liver sections (5 μm) were stained with H&E. Arrow: PMN. Scale bar = 50 μm. Disease scores were evaluated and plotted. *p < 0.05. ***p < 0.001. Data were pooled from three independent experiments.