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. 2015 May 21;10:3699–3717. doi: 10.2147/IJN.S81650

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© 2015 Qin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effect of free-Tan IIA (A) and Tan IIA-NPs (B) on the ratio of tPA/PAI-1 in HMrSV5 cells induced by TGF-β1.

Notes: High, medium and low dose groups were treated with 20, 10, and 5 μg/mL Tan IIA-NPs, respectively. And free-Tan IIA group was treated with 20 μg/mL Tan IIA. Data are expressed as mean ± standard deviation (n=3). *P<0.05 compared with control; ^#P<0.05 compared with model; ^§P<0.05 compared with blank.

Abbreviations: NPs, nanoparticles; Tan IIA, tanshinone IIA; Tan IIA-NPs, Tan IIA liquid NPs; PAI-1, plasminogen activator inhibitor-1; TGF-β1, transforming growth factor-β1; tPA, tissue-type plasminogen activator.