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. 2015 May 21;10:3699–3717. doi: 10.2147/IJN.S81650

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© 2015 Qin et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effects of tPA activity in intraperitoneal lavage fluid.

Notes: High, medium and low dose groups were administered with 10, 5 and 2.5 mg/kg Tan IIA-NPs via tail vein injection, respectively. High- (n=15), medium(n=15), and low-dose (n=15) groups showed a significant increase in tPA activity in peritoneal fluid compared with the control, blank, and drug-free NP groups. *P<0.05 compared with blank; ^#P<0.05 compared with control; ^§P<0.05 compared with drug-free NPs.

Abbreviations: NPs, nanoparticles; tPA, tissue-type plasminogen activator.