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. Author manuscript; available in PMC: 2015 May 27.
Published in final edited form as: Diabetes Res Clin Pract. 2010 May 31;89(3):243–249. doi: 10.1016/j.diabres.2010.04.025

Fig. 1.

Fig. 1

Schematic of the proposed PK/PD model. G represents the glucose; IR, IRR and I represent reserved insulin, readily releasable insulin and plasma insulin respectively. E denotes the extraction ratio of insulin by liver. kG, ke and kRR are rate constants; C50, Emax and α are the parameters in the Hill equation.