Table 1.
Behavioral and cognitive disorders associated with cerebellar lesions reported in neurosurgical case series
| First Author | Year | Age of patients in cohort | Kind of lesion (Number of subjects) | Treatment | Observed disorders |
|---|---|---|---|---|---|
| Morgan AT | 2011 | Pediatric | Pilocytic astrocytoma (n = 7) | Microsurgery, chemotherapy, radiotherapy | Mild dysarthria |
| Medulloblastomas (n = 6) | |||||
| Aarsen FK | 2009 | Pediatric | Pilocytic astrocytomas of the cerebellum (n = 29) | Microsurgery, chemotherapy, radiotherapy | Deficits in verbal intelligence, visual-spatial memory, executive functioning, naming and problems with sustained attention and speed. |
| Puget S | 2009 | Pediatric | Malignant posterior fossa tumors (n = 61) | Microsurgery, chemotherapy, radiotherapy | Low cognitive performances |
| De Ribaupierre S | 2008 | Adult | Various primary and secondary cerebellar tumors (n = 16) | Microsurgery | Severe memory deficits |
| Kotil K | 2008 | Pediatric | Medulloblastoma (N = 20) | Microsurgery, chemotherapy, radiotherapy | Cerebellar mutism |
| Low grade astrocytoma (n = 12) | |||||
| Beebe DW | 2005 | Pediatric | Cerebellar low grade astrocytomas (N = 103) | Microsurgery | Cognitive and adaptive impairment |
| Aarsen FK | 2004 | Pediatric | Pilocytic astrocytomas of the cerebellum (n = 23) | Microsurgery | Apraxia, motor neglect, dysarthria, language, sustained attention, visospatial, executive and memory problems. |
| Behavioral disorders: disinhibition, hypospontaneousness, flattened affects, stickiness, anxiousness, rigidity, Asperger disorder, nightmares, posttraumatic stress and attention deficit and hyperactivity disorder. | |||||
| Gottwald B | 2004 | Adult | Various primary and secondary tumors (n = 17), Hematomas (n = 4) | Microsurgery | Deficits in executive function, attentional processes working memory and divided attention. |
| Ronning C | 2004 | Pediatric | Cerebellar astrocytomas and medulloblastomas | Microsurgery, chemotherapy, radiotherapy | Impaired intelligence, attention, psychomotor speed, verbal memory and visual memory. |
| Gottwald B | 2003 | Adult | Tumors (n = 13), Hematomas (n = 3) | Microsurgery | Attention and working memory deficits |
| Steinlin M | 2003 | Pediatric | Benign cerebellar tumors (n = 24) | Microsurgery | Significant problems for attention, memory, processing speed and interference. Attention deficits, mutism, addiction problems, anorexia, uncontrolled temper tantrums and phobia. |
| Silveri MC | 1998 | Adult | Medulloblastoma of the right cerebellar hemisphere (n = 1) | Microsurgery | Impairment of the immediate retention of verbal information. |