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. 2015 May 27;10(5):e0128293. doi: 10.1371/journal.pone.0128293

Table 3. Plasma Concentrations of compounds of protein glycation and oxidation.

Analyte Women with normal fasting glucose Women with impaired fasting glucose p* p**
Precursor molecule
FruLys [mM] 3.5 (3.2; 3.8) 3.7 (3.2; 4.0) 0.3866 0.2982
Free metabolites
3-DF [μM] 2.7 (2.4; 3.7) 2.4 (1.9; 2.9) 0.1836 0.3058
3-DPs [nM] 18.8 (16.0; 21.1) 17.6 (13.5; 20.3) 0.0846 0.1283
3-DP [nM] 705.1 (389.9; 832.3) 720.3 (424.3; 912.9) 0.4756 0.5446
Hydroimidazolones
MGH1 [nmol/mmol Arg] 178.0 (104.2; 222.6) 200.8 (162.1; 259.3) 0.0763 0.0765
3-DGH [nmol/mmol Arg] 74.8 (28.5; 108.9) 62.5 (28.5; 104.8) 0.9544 0.9012
Oxidated adducts
CML [nM] 676.6 (554.1; 804.5) 688.0 (599.1; 809.7) 0.4400 0.4505
CEL [nM] 152.8 (137.1; 173.4) 169.0 (135.9; 131.3) 0.1409 0.1669
MetSO [mM] 2.1 (1.7; 3.2) 2.5 (1.7; 2.9) 0.8267 0.9188

Data are given as median with 25th and 75th percentiles;

* unadjusted p value;

** p value adjusted for age, BMI, smoking status, passive smoking and education.

3-DF, 3-deoxyfructose; 3-DPs, 3-deoxypentosone; 3-DP, 3-deoxypentulose; MGH1, methylglyoxal-derived hydroimidazolone 1; 3-DGH, 3-deoxyglucosone-derived hydroimidazolone; CML, carboxymethyl lysine; CEL, carboxyethyl lysine; MetSO, methionine sulfoxide; FruLys, Nε-fructosyllysine.