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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Cancer Chemother Pharmacol. 2014 Oct 28;75(1):59–66. doi: 10.1007/s00280-014-2613-7

Fig. 2.

Fig. 2

Course of platelet count following HD-MTX in relation to TPMT activity and coadministered 6MP dose

The course is conditional on an observed platelet count of 250 ×109/L at the day of administration of HD-MTX. The plot depicts patients receiving a 6MP dose of 50-75 mg/m2/day. P value for test of no effect of TPMT on courses of platelet count after HD-MTX: P=0.006. P value for test of no effect of 6MP dose on courses of platelet count after HD-MTX: P<0.001.