Table 1.
Enriched GO terms of genes upregulated in VMN compared to H
| GO category | GO term | Name | FDR |
|---|---|---|---|
| Biological process | GO:0006412 | Translation | 2.90E-18 |
| GO:0006119 | Oxidative phosphorylation | 3.60E-18 | |
| GO:0022900 | Electron transport chain | 8.20E-18 | |
| GO:0042775 | Mitochondrial ATP synthesis coupled electron transport | 1.60E-17 | |
| GO:0042773 | ATP synthesis coupled electron transport | 1.60E-17 | |
| GO:0022904 | Respiratory electron transport chain | 2.30E-17 | |
| GO:0045333 | Cellular respiration | 2.30E-17 | |
| GO:0044283 | Small molecule biosynthetic process | 3.10E-15 | |
| GO:0055114 | Oxidation-reduction process | 5.10E-15 | |
| GO:0044711 | Single-organism biosynthetic process | 7.40E-15 | |
| Molecular function | GO:0003735 | Structural constituent of ribosome | 2.30E-17 |
| GO:0016491 | Oxidoreductase activity | 1.90E-15 | |
| GO:0003954 | NADH dehydrogenase activity | 6.20E-10 | |
| GO:0050136 | NADH dehydrogenase (quinone) activity | 6.20E-10 | |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 6.20E-10 | |
| GO:0015078 | Hydrogen ion transmembrane transporter activity | 1.70E-07 | |
| GO:0016655 | Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 3.50E-07 | |
| GO:0015002 | Heme-copper terminal oxidase activity | 3.80E-07 | |
| GO:0016676 | Oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor | 3.80E-07 | |
| GO:0016675 | Oxidoreductase activity, acting on a heme group of donors | 3.80E-07 | |
| Cellular component | GO:0005739 | Mitochondrion | 8.80E-53 |
| GO:0044429 | Mitochondrial part | 1.20E-22 | |
| GO:0044444 | Cytoplasmic part | 1.70E-21 | |
| GO:0005840 | Ribosome | 2.10E-21 | |
| GO:0005743 | Mitochondrial inner membrane | 4.40E-20 | |
| GO:0019866 | Organelle inner membrane | 6.10E-19 | |
| GO:0070469 | Respiratory chain | 1.50E-16 | |
| GO:0005740 | Mitochondrial envelope | 1.50E-16 | |
| GO:0030529 | Ribonucleoprotein complex | 2.50E-16 | |
| GO:0005737 | Cytoplasm | 3.00E-16 |
Significantly over represented gene ontology (GO) terms found in transcripts upregulated in VMN compared to the surrounding hindbrain (H). Top 10 GO terms from each GO category (biological process, molecular function, and cellular component) are listed in order of decreasing significance by false discovery rate (FDR).