Table 3.
KEGG pathways mapped to transcripts differentially upregulated in VMN vs. H
| VMN | H | ||
|---|---|---|---|
| Pathway | # seqs | Pathway | # seqs |
| Purine metabolism | 60 | Phosphatidylinositol signaling system | 19 |
| Pyrimidine metabolism | 29 | Glycerophospholipid metabolism | 15 |
| Oxidative phosphorylation | 28 | Purine metabolism | 12 |
| Aminoacyl-tRNA biosynthesis | 25 | Lysine degradation | 12 |
| Carbon fixation pathways in prokaryotes | 16 | Glycerolipid metabolism | 11 |
| Pyruvate metabolism | 16 | T cell receptor signaling pathway | 9 |
| Valine, leucine and isoleucine degradation | 14 | Inositol phosphate metabolism | 7 |
| Citrate cycle (TCA cycle) | 13 | Alanine, aspartate and glutamate metabolism | 4 |
| Porphyrin and chlorophyll metabolism | 13 | Arginine and proline metabolism | 3 |
| Glycolysis/Gluconeogenesis | 13 | Fatty acid biosynthesis | 3 |
| Glutathione metabolism | 11 | Glutathione metabolism | 0 |
| Steroid hormone biosynthesis | 7 | Steroid hormone biosynthesis | 0 |
| Steroid biosynthesis | 5 | Steroid biosynthesis | 0 |
| Steroid degradation | 3 | Steroid degradation | 0 |
Top 10 KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways with the highest number of mapped transcripts that were upregulated in VMN or H. Additionally, we show that more transcripts upregulated in VMN are mapped to glutathione methabolism, steroid and steroid hormone biosynthesis pathways.