Figure 1.
Proteins from A431 cell extracts bind to fibulin-1. A431 cell extract was passed over fibulin-1 sepharose column. Eight-molar urea was used to elute the fractions. Fractions were run on 4–12% Tris Glycine SDS-PAGE gel then stained with Coomassie blue. The three major bands were sent for sequencing at the MUSC Mass Spectroscopy Facility and identified as MYH9 (200 Kda), fibulin-1 (75 Kda) and actin (42 Kda). FT, flow-through; STD, molecular weight standards; arrowheads depict major eluted proteins.