A) Immunofluorescence analysis of CAP-D3 (green) and DAPI (blue) staining of colonic tissue from a control patient. B) Immunoblotting for CAP-D3 protein in epithelial cells isolated from resected colon tissue from control patients, patients with inactive CD, active CD, inactive UC, or active UC shows CAPD3 is significantly lower in patients with active UC. Protein levels normalized to villin, then quantified relative to a control sample. Mean±SEM.