Figure 2. RSV attenuates E-selectin and ICAM-1 expression in small intestinal tissue.
We show the E-selectin and ICAM-1 expression in small intestinal tissue sections were studied using immunohistochemistry (20× magnification) in WT and ob/ob mice. E-selectin expression in Sepsis + Vehicle group was significantly increased vs. Sham + Vehicle group in both, WT (2A) and ob/ob (2B) strains. Sepsis + RSV groups had significantly decreased E-selectin expression compared to Sepsis + Vehicle in both WT and ob/ob strains.
We show ICAM-1 expression in small intestinal tissue sections in WT (Figure 2C) and ob/ob (Figure 2D) mice. Similar to E-selectin expression, ICAM-1 expression in Sepsis + Vehicle group were significantly increased vs. Sham + Vehicle group in both, WT and ob/ob tissue sections. Sepsis + RSV groups had significantly decreased ICAM-1 expression compared to Sepsis + Vehicle in both WT and ob/ob strains.