Skip to main content
. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Steroids. 2014 Dec 25;99(0 0):84–90. doi: 10.1016/j.steroids.2014.12.005

Scheme 1.

Scheme 1

Schematic showing the derivatization reactions of 2OH-E2 with dansyl chloride (DSCl), picolinoyl chloride (PCl) or picolinic acid (PA) condensation mixture, pyridine-3-sulfonyl chloride (PSCl), and 1-methylimidazole-2-sulfonyl chloride (ISCl) DSCl: dansyl chloride; PCl: picolinoyl chloride; RT: room temperature; PA: picolinic acid; MNBA: 2-methyl-6-nitrobenzoic anhydride; DMAP: 4-dimethylaminopyridine; Pyr: pyridine; TEA: triethylamine; PSCl: pyridine-3-sulfonyl chloride; ISCl: 1-methylimidazole-2-sulfonyl chloride.