Table 4.

Skeletal Measures (Unadjusted) for the Entire Sample (mean±sd, unless noted otherwise) and Split Based on MPH Treatment Status (mean±se, unless noted otherwise)

	Entire Sample	No-MPH	MPH-Cont	MPH-Intermit	Statistic	p-value
Dual-Energy X-ray Absorptiometry-Based Measures
LS BMC Z-score, n=140	0.11±0.89	−0.25±0.16	0.10±0.11	0.38±0.13	F=4.61	<0.02
LS aBMD Z-score, n=140	0.24±0.98	−0.01±0.18	0.16±0.12	0.53±0.15	F=3.18	<0.05
Low LS aBMD Z-score, n (%), n=140¶	2 (1)	1 (3)	1 (1)	0	Fisher’s Exact	>0.40
TBLH BMC Z-score, n=54	0.09±0.77	−0.27±0.23	0.07±0.15	0.34±0.17	F=2.28	>0.10
TBLH aBMD Z-score, n=54	0.25±0.77	0.06±0.23	0.27±0.16	0.33±0.18	F=0.43	>0.60
Low TBLH aBMD	0	0	0	0	---	---
Z-score, n (%), n=54¶
Peripheral Quantitative Computed Tomography-Based Measures
Trabecular vBMD, mg/cm3, n=150	201±39	200±7	201±5	202±6	F=0.04	>0.90
Total vBMD, mg/cm3, n=150	322±54	322±10	320±6	326±8	F=0.18	>0.80
Strength Index, mg2/mm4, n=150	22.9±11.1	26.4±2.0	23.0±1.3	20.6±1.6	F=2.49	<0.09
Cortical vBMD, mg/cm3, n=35	1060±31	1064±13	1058±8	1062±9	F=0.11	>0.80
Cortical Thickness, mm, n=35	2.3±0.4	2.6±0.2	2.1±0.1	2.2±0.1	F=3.17	<0.06
Endosteal Circumference, mm, n=35	17.4±3.9	18.4±1.6	16.9±1.0	17.4±1.1	F=0.31	>0.70
Periosteal Circumference, mm, n=35	31.5±5.1	34.8±2.1	30.4±1.2	31.4±1.5	F=1.65	>0.20
Polar Section Modulus, mm3, n=35	142±70	192±28	128.7±16	137±19	F=2.02	>0.10

MPH: psychostimulants, LS: lumbar spine, BMC: bone mineral content, aBMD: areal bone mineral density, TBLH: total body less head, vBMD: volumetric bone mineral density.

Age-sex-height-race-specific Z-scores for LS and TBLH BMC and aBMD were generated following the Bone Mineral Density in Childhood Study [30].

^¶Defined as a Z-score ≤ −2.0.

Significant results (p<0.05) are bolded and marginally significant results (p<0.10) are bolded and italicized.