Table 3. Allelic and genotypic frequencies of MTHFR C677T polymorphism.

MTHFR C677T	Cases* N (%)	Controls** N (%)	OR (95%CI)	P
Genotype
CC	46 (49)	49 (49)	Reference
CT	38 (40)	42 (42)	1.04 (0.57–1.88)	0.903
TT	10 (11)	9 (9)	0.84 (0.32–2.27)	0.738
CT+TT	48 (51)	51 (51)	1.00 (0.57–1.75)	0.993
Alelle
C	130 (69)	140 (70)	Reference
T	58 (31)	60 (30)	0.96 (0.62–1.48)	0.856

*Mothers of children with DS; N = 94

**Control mothers; N = 100