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. 2015 May 4;43(10):4785–4799. doi: 10.1093/nar/gkv427

Figure 2.

Figure 2.

(A) Views of the various TTA loop types (coloured as in Figure 1), grouped into 12 distinct categories. (B) (i) The two sub-types of type-1 loops. Sub-type 1 (left) is from PDB structure 1KF1, sub-type 2 (right) is from PDB structure 3T5E. The structures shown here have been structurally aligned and are presented in the same orientation. (ii) An example of the structural diversity of non-type-1 loops: overlay of a type-4 loop (pink, from PDB structure 3CCO), a type-10 loop (green, from PDB structure 3SC8) and a type-1 loop (red, from PDB structure 1KF1). The non-type-1 loops are dramatically different to the ‘native’ type-1 TTA loop—as well as to one another. Note the retention of base-stacking interactions in the type-10 loop arrangement, which is a common feature of non-type-1 loops.